Tolvaptan CAS 150683-30-0 Uruganda rwa API rwiza

Ibisobanuro bigufi:

Izina ryimiti: Tolvaptan

URUBANZA: 150683-30-0

Suzuma (HPLC): 98.0 ~ 102.0%

Kugaragara: Umweru to Off-White Crystalline Powder

Vasopressine ikomeye kandi ihitamo V2 reseptor antagonist

API Ubwiza buhanitse, Umusaruro wubucuruzi

Kubaza: alvin@ruifuchem.com


Ibisobanuro birambuye

Ibicuruzwa bifitanye isano

Ibiranga ibicuruzwa

Ibisobanuro:

Gutanga ibicuruzwa
Ubwiza buhanitse, Umusaruro wubucuruzi
Izina ryimiti: Tolvaptan
URUBANZA: 150683-30-0

Ibikoresho bya Shimi:

Izina Tolvaptan
Izina ryimiti N- [4- (9-chloro-6-hydroxy-2-azabicyclo [54.0]
Numero ya CAS 150683-30-0
Inomero y'injangwe RF-API101
Imiterere yimigabane Mububiko, Igipimo cyumusaruro kugeza kuri Toni
Inzira ya molekulari C26H25ClN2O3
Uburemere bwa molekile 448.94
Ikirango Ruifu

Ibisobanuro:

Ingingo Ibisobanuro
Kugaragara Umweru Kuri Off-Yera Ifu ya Crystalline
Uburyo bwo Kumenyekanisha IR, HPLC
Suzuma (HPLC) 98.0 ~ 102.0% (ku buryo budasanzwe)
Ingingo yo gushonga 219.0 ~ 222.0 ℃
Gutakaza Kuma ≤0.50%
Ibisigisigi kuri Ignition ≤0.10%
Umwanda umwe ≤0.50%
Impanuka zose ≤1.0%
Ibyuma biremereye ≤20ppm
Ibisubizo bisigaye Hura Ibisobanuro
Ikizamini Ibipimo ngenderwaho
Ikoreshwa Imiti ya farumasi

Amapaki & Ububiko:

Amapaki: Icupa, umufuka wa aluminium, 25kg / Ikarito yingoma, cyangwa ukurikije ibyo umukiriya asabwa.

Imiterere yo kubika:Bika mu bikoresho bifunze ahantu hakonje kandi humye;Irinde urumuri nubushuhe.

Ibyiza:

1

Ibibazo:

Gusaba:

Tolvaptan (CAS 150683-30-0), izwi kandi ku izina rya OPC-41061, ni uburyo bwo guhitamo, guhatanira arginine vasopressine reseptor 2 antagonist ikoreshwa mu kuvura hyponatremia (urugero rwa sodium nkeya mu maraso) ifitanye isano no kunanirwa k'umutima, cirrhose, na syndrome idakwiye. imisemburo ya antidiuretic (SIADH).Otsuka Pharmaceutical yemereye tolvaptan ku izina ryubucuruzi Samsca nyuma yuko FDA yemeye ibiyobyabwenge muri Gicurasi 2009. Tolvaptan yerekanye kandi imbaraga zo kurwanya indwara yimpyiko.Mu igeragezwa ryo mu 2004, tolvaptan yatanzwe hamwe na diuretique gakondo byagaragaye ko byongera gusohora amazi menshi kandi bikongera urugero rwa sodium mu maraso ku barwayi bafite ikibazo cy'umutima bitagize ingaruka mbi nka hypotension (umuvuduko ukabije w'amaraso) cyangwa hypokalemia (igabanuka ry'amaraso ya potasiyumu).Uyu muti kandi nta ngaruka mbi wagize ku mikorere y'impyiko.

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